{"id":4389,"date":"2020-01-10T15:06:56","date_gmt":"2020-01-10T14:06:56","guid":{"rendered":"https:\/\/biopharmatec.com\/comprimes-a-deux-couches\/"},"modified":"2025-11-03T15:16:46","modified_gmt":"2025-11-03T14:16:46","slug":"comprimes-a-deux-couches","status":"publish","type":"page","link":"https:\/\/biopharmatec.com\/fr\/comprimes\/comprimes-a-deux-couches\/","title":{"rendered":"Comprim\u00e9s \u00e0 deux couches"},"content":{"rendered":"

[et_pb_section fb_built=\u00a0\u00bb1″ module_class=\u00a0\u00bbsatag-header-background\u00a0\u00bb _builder_version=\u00a0\u00bb4.27.4″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_image=\u00a0\u00bbhttps:\/\/biopharmatec.com\/wp-content\/uploads\/2025\/04\/zweischichttabletten.jpg\u00a0\u00bb animation_style=\u00a0\u00bbslide\u00a0\u00bb animation_direction=\u00a0\u00bbtop\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb4.17.6″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_enable_image=\u00a0\u00bboff\u00a0\u00bb width=\u00a0\u00bb100%\u00a0\u00bb max_width=\u00a0\u00bb2560px\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.17.6″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_enable_image=\u00a0\u00bboff\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00a0\u00bb1″ _builder_version=\u00a0\u00bb4.17.6″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb animation_style=\u00a0\u00bbslide\u00a0\u00bb animation_direction=\u00a0\u00bbbottom\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_row _builder_version=\u00a0\u00bb4.17.6″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.17.6″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.17.6″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

Comprim\u00e9s \u00e0 deux couches<\/h1>\n

BioPharmatec a la possibilit\u00e9 de comprimer deux m\u00e9langes de poudres distincts en un seul comprim\u00e9. Cela permet par exemple d’avoir une tablette de deux couleurs, ou d’utiliser des m\u00e9langes de mati\u00e8res premi\u00e8res qui ne se combineraient pas bien dans un m\u00e9lange. <\/p>\n

L’ajout d’une couche suppl\u00e9mentaire est une t\u00e2che stimulante. La couche pr\u00e9c\u00e9dente doit \u00eatre pr\u00e9par\u00e9e pour former un lien avec la couche suivante, tout en garantissant une ligne de s\u00e9paration parfaite entre les deux couches. Un comprim\u00e9 dont les diff\u00e9rentes couches contiennent des principes actifs et des profils de lib\u00e9ration diff\u00e9rents pr\u00e9sente un avantage th\u00e9rapeutique \u00e9vident. <\/p>\n

La technologie de lib\u00e9ration contr\u00f4l\u00e9e ou retard\u00e9e du principe actif est plus avantageuse que le comprim\u00e9 monocouche. Les comprim\u00e9s \u00e0 deux couches peuvent \u00eatre constitu\u00e9s d’une structure monolithique, partiellement enrob\u00e9e ou multicouche. <\/p>\n

Particularit\u00e9s des comprim\u00e9s \u00e0 deux couches<\/h2>\n

L’utilisation de comprim\u00e9s \u00e0 deux couches augmente, on y a recours lorsque deux substances actives ne peuvent pas \u00eatre associ\u00e9es, par exemple en raison d’une lib\u00e9ration diff\u00e9rente de la substance active. L’utilisation de deux stations de remplissage pr\u00e9pare la machine \u00e0 la production en deux \u00e9quipes. Le comprim\u00e9 doit \u00eatre pr\u00e9-comprim\u00e9 dans la premi\u00e8re \u00e9tape avant que la premi\u00e8re couche avec le deuxi\u00e8me composant actif puisse \u00eatre comprim\u00e9e de mani\u00e8re stable pour former un comprim\u00e9 de deuxi\u00e8me couche. <\/p>\n

Vous avez besoin de conseils sur le type de tablette adapt\u00e9 \u00e0 votre produit ?<\/p>\n

 <\/p>\n

Demander un devis<\/a><\/span><\/p>\n

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Contact<\/span><\/p>\n

06242 900910<\/span><\/a><\/p>\n

Demander un devis<\/a><\/span><\/p>\n

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Comprim\u00e9s \u00e0 deux couches BioPharmatec a la possibilit\u00e9 de comprimer deux m\u00e9langes de poudres distincts en un seul comprim\u00e9. Cela permet par exemple d’avoir une tablette de deux couleurs, ou d’utiliser des m\u00e9langes de mati\u00e8res premi\u00e8res qui ne se combineraient pas bien dans un m\u00e9lange. L’ajout d’une couche suppl\u00e9mentaire est une t\u00e2che stimulante. La couche […]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":11624,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","inline_featured_image":false,"footnotes":""},"class_list":["post-4389","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/pages\/4389","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/comments?post=4389"}],"version-history":[{"count":20,"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/pages\/4389\/revisions"}],"predecessor-version":[{"id":13998,"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/pages\/4389\/revisions\/13998"}],"up":[{"embeddable":true,"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/pages\/11624"}],"wp:attachment":[{"href":"https:\/\/biopharmatec.com\/fr\/wp-json\/wp\/v2\/media?parent=4389"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}